Health & Wellness · Head-to-head
Resmed AirFit F20 Cushion vs resplabs CPAP Mask Wipes, Unscented
Which should you buy? Our verdict on both, pulled from our full The Best CPAP Cleaning Supplies: 4 Compared (and One to Skip) comparison.
Replacing the cushion on schedule does more for mask hygiene and seal quality than any sanitizing machine, and it is the one CPAP part that genuinely wears out against your skin every night. Pair it with unscented wipes for daily upkeep and you have covered what the FDA and the mask manufacturers actually ask for.

Resmed AirFit F20 Cushion
Buy itThe genuine silicone replacement cushion for the AirFit F20 full face mask, and the single most useful thing most CPAP users can spend money on for hygiene.
- Resmed's own replacement guidance says a full face cushion may need replacing as often as every month, which makes this the part that keeps a mask hygienic.
- Silicone washes clean with mild detergent and warm water, exactly the method Resmed and the FDA both describe.
- Sold in small, medium and large so an existing frame and headgear carry over.
- It is a mask part, not a cleaning device, so it does nothing for tubing or the humidifier tub.
- Only fits the AirFit F20 family, so owners of nasal or pillow masks need the equivalent cushion for their own mask.
- Buying cushions at the recommended cadence adds up over a year if insurance does not cover resupply.

resplabs CPAP Mask Wipes, Unscented
Buy itA canister of unscented, alcohol free cotton wipes for the daily face oil and sweat that builds up on a cushion between proper washes.
- Unscented and alcohol free, which matters because Resmed's cleaning FAQ specifically discourages strong smelling products on mask parts.
- Works on full face, nasal and nasal pillow cushions, so it is not tied to one mask family.
- A canister of 110 lasts roughly a quarter at one wipe per morning, which makes daily upkeep realistic.
- A wipe is upkeep, not cleaning, and it does not substitute for the weekly wash the mask makers describe.
- Cannot reach the inside of tubing, which is the part hardest to clean and the part the FDA says has never been shown to be adequately cleaned by ozone or UV.
- No FDA authorization exists for wipes as a disinfection step, and none is claimed.
Side by side
| Resmed AirFit F20 Cushion | resplabs CPAP Mask Wipes, Unscented | |
|---|---|---|
| Our verdict | Buy | Buy |
| Best for | AirFit F20 users who want the biggest real hygiene improvement available and are currently stretching one cushion across many months. | Anyone who wants their mask to feel clean every morning without a sink ritual, as a supplement to a proper weekly wash. |
| Price tier | $$ · mid-range | $ · budget |
The bottom line
Our overall pick is the Resmed AirFit F20 Cushion - The genuine silicone replacement cushion for the AirFit F20 full face mask, and the single most useful thing most CPAP users can spend money on for hygiene. Choose the resplabs CPAP Mask Wipes, Unscented instead if anyone who wants their mask to feel clean every morning without a sink ritual, as a supplement to a proper weekly wash.
Want the full picture, including the other options we compared and the popular one we'd skip? Read the complete The Best CPAP Cleaning Supplies: 4 Compared (and One to Skip).