Beauty & Grooming · Head-to-head
Opalescence Go 15% Prefilled Whitening Trays vs GLO Science So Brilliant Teeth Whitening Kit
Which should you buy? Our verdict on both, pulled from our full The Best At-Home Teeth Whitening Kits: 4 Compared (and One to Skip) comparison.
The Opalescence Go trays are the best all-round pick: 15% hydrogen peroxide in prefilled trays you wear for 15 to 20 minutes a day, with no device to charge. The GLO So Brilliant is the gentle, premium alternative worth the extra outlay if sensitivity is your main concern.

Opalescence Go 15% Prefilled Whitening Trays
Buy itPrefilled 15% hydrogen peroxide trays from a dental whitening brand, worn for 15 to 20 minutes a day.
- 15% hydrogen peroxide, which Opalescence says whitens up to 5 shades in 10 days when used as directed
- Prefilled UltraFit trays that flex to fit, work with braces, and need only 15 to 20 minutes of wear a day
- The gel contains potassium nitrate and sodium fluoride, and a gentler 10% version is offered for sensitive teeth
- Opalescence warns of possible temporary discomfort of the gums, lips, throat, tongue or teeth, and says to stop and see a dentist if sensitivity is significant
- A box is 10 treatments, the trays are one-size rather than custom, and they are not for children under 12

GLO Science So Brilliant Teeth Whitening Kit
Buy itA dentist-designed warming mouthpiece that pairs gentle heat with light, aimed squarely at sensitive teeth.
- Warming-plus-light mouthpiece is what owners credit for low reported sensitivity
- Gel with 6% hydrogen peroxide is brushed onto the visible teeth, then the mouthpiece warms it
- Comes with a carry case, a charging cable and five gel pods
- The most expensive option here by a wide margin
- More steps and gel pods to manage than a simple one-piece kit
Side by side
The 7 criteria below are the ones our full comparison judged every product on, narrowed to these two.
| Opalescence Go 15% Prefilled Whitening Trays Our pick | GLO Science So Brilliant Teeth Whitening Kit | |
|---|---|---|
| Our verdict | Buy | Buy |
| Best for | Most people who want meaningful whitening at home from a dental brand, with no device to charge. | Sensitive-teeth users, and anyone who wants a premium, gentle device and will pay for it. |
| Price tier | $$$ · premium | $$$$ · flagship |
| Whitening method | Prefilled UltraFit trays | Warming mouthpiece + LED |
| Active approach | 15% hydrogen peroxide | 6% hydrogen peroxide gel pods |
| Real shade change | Up to 5 shades in 10 days, per Opalescence | Yes, per owner reports |
| Sensitivity-friendly | Potassium nitrate; 10% version for sensitivity | Gentle heat; maker claims little to no sensitivity |
| Effort per session | Low, 15 to 20 minutes, no device | Moderate, more steps |
| Portability | Excellent | Good, full case |
| Best use | Main whitening | Gentle premium whitening |
Which one is right for you?
Pick the Opalescence Go 15% Prefilled Whitening Trays if
most people who want meaningful whitening at home from a dental brand, with no device to charge.
Know before buying: opalescence warns of possible temporary discomfort of the gums, lips, throat, tongue or teeth, and says to stop and see a dentist if sensitivity is significant.
Pick the GLO Science So Brilliant Teeth Whitening Kit if
sensitive-teeth users, and anyone who wants a premium, gentle device and will pay for it.
Know before buying: the most expensive option here by a wide margin.
The bottom line
Our overall pick is the Opalescence Go 15% Prefilled Whitening Trays - Prefilled 15% hydrogen peroxide trays from a dental whitening brand, worn for 15 to 20 minutes a day. Choose the GLO Science So Brilliant Teeth Whitening Kit instead if sensitive-teeth users, and anyone who wants a premium, gentle device and will pay for it.
Want the full picture, including the other options we compared and the popular one we'd skip? Read the complete The Best At-Home Teeth Whitening Kits: 4 Compared (and One to Skip).